Why Is My Dog's Nose Turning Black. Some dog's noses change colors from a dark color to pink in cold weather; It slowly started turning grey/white/pinkish from black, over a period of about a month and a half. Now, it has taken over her entire nose. This is thought to be a result of the breakdown of tyrosinase, which is an enzyme that produces … It is important that you know all the reasons why it is that this discoloration can occur to take preventive measures. It is important that you know all the reasons why it is that this discoloration can occur to take preventive measures. 6/7/2006 · tyrosine acts via an enzyme catalyst called tyrosinase. Dogs are known to repeat this. This may be due to a poor diet, an autoimmune disease, allergies, and even to a skin cancer.This may be due to a poor diet, an autoimmune disease, allergies, and even to a skin cancer.
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